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Effekten varer bare noen fileå timer, og det kan ta uker eller måneder før maksimal effekt oppnås (8). Bivirkninger, for eksempel svetting, er vanlig, Gentlemen er oftest milde og tolerable. Pilokarpin bør ikke gis til pasienter med ukontrollert astma, eller ved trangvinkelglaukom og brukes med forsiktighet ved pulmonal eller kardiovaskulær s